Natural betaine is the best methyl donor because it can be directly used in the transmethylation process without conversion, saving methionine, and reducing toxic homocysteine. Betaine naturally adds three methyl groups and glycine to the transmethylation cycle. Glycine, an important amino acid that is not bound, is also important.
This is the main fact about methylation and why natural betaine makes the best choice for the methyl donor for animal feed.
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S-adenosyl-methionine (SAM) is part of the transmethylation cycle that provides methyl donors that are important for creating a synthesis, phosphatidylcholine formation, DNA synthesis / RNA, immune modulation, and more other functions in the body.
This tariff limit is only valid for mitochondria. This process means that choline does not meet the body's needs for methyl groups. Therefore Choline is not the best methyl donor for animal feed.
Methionine is used to make choline shortages in animal feed. This is provided by one methyl group to s-adenosyl-methionine. Methionine, the important building block of protein, is the main role that must be played. Methionine should not be removed from the transmethylation cycle. To ensure that methionine is used effectively, it is important to take into account all sulfur amino acids in the feed.
Natural betaine, which recycles homocysteine and methionine during the transmethylation cycle, is the best methyl donor.